Key result
The APACHE II system showed good discrimination for predicting in-hospital mortality (AUC 0.80) but lacked accuracy, with a recorded death rate of 35.5% versus a predicted rate of 25.6%.
Why the study?
Does the APACHE II system accurately predict in-hospital mortality in intensive care unit patients?
Population
521 consecutive patients admitted to a clinical and surgical intensive care unit in a tertiary-care teaching…
Design
Cohort
Follow-up
In-hospital
Authors
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APACHE II may aid ICU risk stratification but underestimates mortality; leaves open need for local validation and recalibration.
Observational (n=521)
No
Does the APACHE II system accurately predict in-hospital mortality in intensive care unit patients?
Effect estimate: AUC 0.80
Absolute Event Rate: 25.6% vs 35.5%
While the APACHE II score provides good discrimination for stratifying ICU patients by illness severity, it underestimates the actual in-hospital mortality rate in this cohort.
Chiavone et al. (2003) conducted an observational in Intensive care patients (n=521). APACHE II system was evaluated on In-hospital mortality (AUC 0.80). The APACHE II system showed good discrimination for predicting in-hospital mortality (AUC 0.80) but lacked accuracy, with a recorded death rate of 35.5% versus a predicted rate of 25.6%.
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