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May 1, 1982Journal of Neurology Neurosurgery & PsychiatryOpen Access

Subcortical arteriosclerotic encephalopathy (Binswanger's type) and cortical infarcts in a young normotensive patient.

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Authors

LLL A LoizouSt George's, University of London JJJohn JeffersonCedars-Sinai Medical Center WSWilliam SmithUniversity of Miami

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Implication

Case report reveals significant neurological decline from infarcts in an unusual young normotensive patient, indicating rare vascular issues.

Key Points

To describe the clinical, radiological, and neuropathological features of subcortical arteriosclerotic encephalopathy in a young patient without hypertension.
Case report of a 49-year-old normotensive man with strokes and dementia over 23 years
CT scans analyzed for infarct locations in the cortical and white matter
Neuropathological examination conducted post-mortem to confirm the findings
CT scans revealed large cortical and small subcortical infarcts in the temporo-occipital areas
Neuropathology confirmed hyaline arteriosclerosis impacting small intracerebral arteries
Notable degeneration and demyelination in central white matter corresponded to CT findings

Cite This Study

Loizou et al. (1982) studied this question.

synapsesocial.com/papers/6a1bdda1ea84844e355f1645 https://doi.org/10.1136/jnnp.45.5.409

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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1Subcortical arteriosclerotic encephalopathy (Binswanger's disease). A vascular etiology of dementia.1976 · 59 citations
2Subcortical arteriosclerotic encephalopathy (Binswanger)1979 · 134 citations
3Predominant White Matter Involvement in Subcortical Arteriosclerotic Encephalopathy (Binswanger Disease)1980 · 106 citations
4Clinical features of subcortical arteriosclerotic encephalopathy (Binswanger disease)1978 · 283 citations