Why the study?
Cardiac catheter ablation carries a risk of thromboembolism from thrombosis on guidewires, ablation catheters, and sheaths.
Does a novel anti-thrombogenic coating reduce the rate of clot formation on indwelling intravascular devices during intra-cardiac ablation?
Does a novel anti-thrombogenic coating reduce the rate of clot formation on indwelling intravascular devices during intra-cardiac ablation?
A novel anti-thrombogenic coating was developed and tested to potentially reduce device-related thrombosis during cardiac catheter ablation.
Hypothesis-generating for coated devices in ablation; human trials needed before clinical consideration.
Background: Cardiac catheter ablation is associated with risk of thromboembolism such as stroke. Potential sources of embolism include thrombosis on guidewires, ablation catheters, and sheaths. In this study, we developed and tested a novel anti-thrombogenic coating to reduce the rate of thrombosis on indwelling intravascular devices.
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Suraj Kapa (2021) studied this question.
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