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June 1, 1991Statistics in Medicine

Interim analysis in clinical trials

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PAP. ArmitageUniversity of Cambridge

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P. Armitage (1991) studied this question.

synapsesocial.com/papers/6a1be6656f692abb725ef5dehttps://doi.org/10.1002/sim.4780100613
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Assessment of the Subjective Opinion and its Use in Relation to Stopping Rules for Clinical Trials1983 · 111 citations
  2. 2Monitoring Treatment Differences in Long-Term Clinical Trials1977 · 110 citations