Why the study?
Does aspirin reduce renal function and urinary prostaglandin E excretion in women with systemic lupus erythematosus?
Does aspirin reduce renal function and urinary prostaglandin E excretion in women with systemic lupus erythematosus?
In women with systemic lupus erythematosus, aspirin causes significant, reversible declines in renal function that correlate with decreased urinary prostaglandin E excretion.
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Aspirin may warrant renal monitoring in women with SLE; hypothesis-generating for prostaglandin mediation, needing randomized confirmation.
Kimberly et al. (1978) studied this question.
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