Why the study?
Do high levels of von Willebrand factor predict bleeding complications and mortality in patients receiving oral anticoagulation?
Do high levels of von Willebrand factor predict bleeding complications and mortality in patients receiving oral anticoagulation?
High levels of von Willebrand factor are associated with an increased risk of major bleeding and mortality in patients on oral anticoagulation, complicating its use as a thromboembolic risk marker.
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May flag higher bleeding risk on OAC; hypothesis-generating for VWF in risk stratification.
Lind et al. (2011) studied this question.
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