August 1, 1982Angiology
Calcium Antagonists in the Treatment of Individuals with Ischemic Heart Disease
Why the study?
Are calcium antagonists effective in the treatment of individuals with ischemic heart disease?
Population
Individuals with ischemic heart disease, including Prinzmetal's variant angina pectoris, stable angina…
Design
Review
Authors
Discussion
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Member takes
Implication
Supports calcium antagonist use across angina types; extends early observations but leaves open need for modern RCTs.
Structured PICO
Are calcium antagonists effective in the treatment of individuals with ischemic heart disease?
P
Population
Individuals with ischemic heart disease, including Prinzmetal's variant angina pectoris, stable (exertional) angina pectoris, unstable angina pectoris, acute myocardial infarction, and those undergoing cardiopulmonary bypass
I
Intervention
Calcium antagonists (verapamil, nifedipine, diltiazem, and perhexiline)
This review outlines the mechanisms and clinical utility of calcium antagonists in managing various forms of ischemic heart disease.
Cite This Study
Winniford et al. (1982) studied this question.