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January 1, 1995Thrombosis and Haemostasis

Issues in the Development of Thrombin Receptor Antagonists

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Authors

LBLawrence F. BrassCross-Cutting Cardiology

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Implication

Broadens thrombin receptor antagonist potential beyond platelets; leaves open therapeutic exploration in vascular and CNS disorders.

Structured PICO

I
Intervention
Thrombin receptor antagonists

The development of thrombin receptor antagonists may have broader clinical applications beyond anti-platelet therapy due to the presence of these receptors on various cell types.

Cite This Study

Lawrence F. Brass (1995) studied this question.

synapsesocial.com/papers/6a1bf08d4ebd09f3dfa93b55https://doi.org/10.1055/s-0038-1642728
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Thrombin receptor (PAR-1) antagonists as novel antithrombotic agents2006 · 26 citations
  2. 2Trafficking thrombin receptors1995 · 6 citations
  3. 3Thromboxane A 2 Receptor2011 · 34 citations
  4. 4Non-Peptidic Small-Molecule Antagonists of the Human Platelet Thrombin Receptor PAR-12003 · 10 citations
  5. 5Recent Development in Thrombin Receptor Antagonist as Novel Antithrombotic Agent2012 · 1 citations