Why the study?
Several models have been proposed to characterize diastolic function and tissue Doppler e′-wave velocity, but the parametrized diastolic filling (PDF) and force balance model (FBM) had not been previously compared.
Population
Published FBM-generated e′(t) contours
Comparison
Parametrized diastolic filling (PDF) model vs force balance model (FBM)
Design
Mathematical and numerical modeling analysis
Authors
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Model equivalence bolsters oscillatory diastolic descriptions; leaves open empirical validation before clinical translation.
Two separate physiological models predict mathematically identical expressions for LV-lengthening velocity, indicating that damped harmonic oscillatory motion is a physiologically accurate model of diastolic function.
Bhagavan et al. (2020) studied this question.
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