Key points are not available for this paper at this time.
This article was written at the invitation of the Editor, in response to the preceding article by Strother et aI. (1995). I have taken this opportunity to comment on several issues, some of which have been the subject of recent exchanges (e.g. , Taylor et aI., 1993; Worsley et aI. , 1993). Others deserve mention because they have become of special cur rent interest. An overview of the development of statistical analysis in functional imaging is pre sented, followed by a discussion of some key areas.
Karl Friston (1995) studied this question.