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April 26, 1999Biochemical JournalOpen Access

Kinetic basis for selective inhibition of cyclo-oxygenases

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Authors

JGJames K. GierseAgricultural Research ServiceCKCarol M. KoboldtSea Turtle ConservancyMWMark C. WalkerMonsanto (United States)

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Cite This Study

Gierse et al. (1999) studied this question.

synapsesocial.com/papers/6a1bf875b33628da419d0fc3https://doi.org/10.1042/bj3390607
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Single Amino Acid Difference between Cyclooxygenase-1 (COX-1) and −2 (COX-2) Reverses the Selectivity of COX-2 Specific Inhibitors1996 · 412 citations
  2. 2Role of Val509 in Time-dependent Inhibition of Human Prostaglandin H Synthase-2 Cyclooxygenase Activity by Isoform-selective Agents1996 · 114 citations
  3. 3The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes.1990 · 943 citations
  4. 4The Dynamics of Prostaglandin H Synthases1998 · 91 citations