Why the study?
Do negative lifestyle factors (physical inactivity, smoking) increase surrogate markers of vascular risk in young people?
Do negative lifestyle factors (physical inactivity, smoking) increase surrogate markers of vascular risk in young people?
Negative lifestyle factors like smoking and physical inactivity in young adults are associated with increased vascular stiffness and stress, indicating early cardiovascular risk.
Pulse wave metrics may flag early vascular changes from smoking or inactivity in youth; hypothesis-generating for clinical events and prospective validation.
The paper presents the results of determining vascular risk due to negative lifestyle factors (physical inactivity, smoking) in young people. The group of respondents (91 people, age 18–20 years) was divided into 3 subgroups depending on the facts of smoking and physical inactivity. The study of endothelium function and elasticity of arterioles was determined using the AngioScan (photo-plethysmographic method for recording the pulse wave) and assessing the shape and state of the capillaries using a capillaroscope (USB microscope series PW200-PW1600). The criteria for vascular risk were: the stiffness of the vascular wall, assessed using the type of pulse wave (A, B, C), tissue saturation with oxygen, the level of vascular «stress» (based on the dynamics of the pulse rate). By comparing these indicators with AngioScan software, the biological age of the vessels was determined. Relative vascular risk was defined as the ratio of the registered indicators in groups 1 and 2 to the corresponding indicators in group 3 (the control group). By calculating the relative vascular risk, the most sensitive indicators were identified: the type of pulse wave and the magnitude of vascular «stress», which indicate a pronounced tendency to unfavorable prognosis of cardiovascular diseases in this lifestyle.
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Tv et al. (2019) studied this question.
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