Key result
A pharmacist-initiated intervention significantly increased planned or actual warfarin use at hospital discharge (OR 2.46) compared to historical controls in patients with non-valvular atrial fibrillation.
Why the study?
Does a pharmacist-initiated intervention improve planned antithrombotic prescribing at discharge in hospitalized patients with non-valvular atrial fibrillation?
Population
252 hospitalized adult patients with non-valvular atrial fibrillation. Excluded: patients serviced by…
Comparison
Pharmacist-initiated intervention consisting of… vs Historical control group receiving routine…
Design
Cohort, Non-blinded intervention; chart review conducted by 2 non-investigator…
Follow-up
At hospital discharge
Authors
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May support pharmacist-led AF discharge planning; hypothesis-generating and requires randomized confirmation.
Observational (n=252)
Non-blinded
No
Does a pharmacist-initiated intervention improve planned antithrombotic prescribing at discharge in hospitalized patients with non-valvular atrial fibrillation?
Effect estimate: OR 2.46 (95% CI 1.63-3.74)
Absolute Event Rate: 78.6% vs 57.1%
p-value: p=<0.01
A pharmacist-initiated inpatient intervention significantly improved the rate of planned antithrombotic therapy, particularly warfarin, at hospital discharge for patients with non-valvular atrial fibrillation.
Touchette et al. (2008) conducted an observational in Non-valvular atrial fibrillation (n=252). Pharmacist-initiated intervention (review and assessment of antithrombotic prescribing) vs. Historical control (routine medical care) was evaluated on Planned or actual warfarin use at discharge (OR 2.46, 95% CI 1.63-3.74, p=<0.01). A pharmacist-initiated intervention significantly increased planned or actual warfarin use at hospital discharge (OR 2.46) compared to historical controls in patients with non-valvular atrial fibrillation.
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