Key result
The addition of phase analysis to evaluate exercise-induced left ventricular mechanical dyssynchrony on conventional perfusion analysis improved sensitivity to 77% and specificity to 88% for identifying multivessel coronary artery disease.
Why the study?
Does the addition of phase analysis of exercise-induced LV mechanical dyssynchrony to conventional perfusion analysis improve the detection of multivessel CAD in patients with suspected or confirmed CAD?
Observational (n=278)
Single-blind
No
Does the addition of phase analysis of exercise-induced LV mechanical dyssynchrony to conventional perfusion analysis improve the detection of multivessel CAD in patients with suspected or confirmed CAD?
Absolute Event Rate: 77% vs 70%
Adding phase analysis of exercise-induced LV mechanical dyssynchrony to conventional SPECT perfusion analysis improves the diagnostic accuracy for detecting multivessel coronary artery disease.
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May aid multivessel CAD detection on SPECT; leaves open prospective validation before clinical adoption.
Hida et al. (2012) conducted an observational in Coronary artery disease (n=278). Phase analysis of exercise-induced left ventricular mechanical dyssynchrony vs. Conventional perfusion analysis alone was evaluated on Sensitivity for identifying multivessel coronary artery disease. The addition of phase analysis to evaluate exercise-induced left ventricular mechanical dyssynchrony on conventional perfusion analysis improved sensitivity to 77% and specificity to 88% for identifying multivessel coronary artery disease.
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