Key result
Electrocardiographic left ventricular hypertrophy was not associated with increased in-hospital mortality (5.4% vs 3.6%) or adverse events in patients with first NSTEMI.
Why the study?
Data regarding the prognostic implication of electrocardiographic left ventricular hypertrophy in patients presenting with a first NSTEMI were conflicting.
Does electrocardiographic left ventricular hypertrophy predict in-hospital adverse events in patients with first NSTEMI?
Cohort (n=460)
No
Does electrocardiographic left ventricular hypertrophy predict in-hospital adverse events in patients with first NSTEMI?
Electrocardiographic left ventricular hypertrophy by Sokolow-Lyon criteria does not predict increased in-hospital adverse events in patients presenting with a first NSTEMI.
May not alter acute risk stratification in first NSTEMI; hypothesis-generating and requires prospective validation.
BACKGROUND: There is conflicting data about prognostic implication of electrocardiographic (ECG) left ventricular hypertrophy (LVH) in patients with first non- ST-segment elevation myocardial infarction (NSTEMI). We aimed to examine the association of left ventricular hypertrophy (LVH) on admission electrocardiogram with adverse outcomes in patients with NSTEMI. METHODS: In the present study, 460 patients (77.5% males with mean age of 65.44±13.15 years) with first NSTEMI were evaluated. ECG left ventricular hypertrophy (LVH) was diagnosed based on Sokolow-Lyon voltage criteria. Baseline laboratory and clinical results, angiographic data, as well as in- hospital adverse events were compared between the patients with and without LVH. RESULTS: Electrocardiographic LVH was observed in 74 (16.1%) patients. Patients with LVH had higher admission systolic blood pressure (132.91±21.08 vs 125.80±21.78; P=0.01) and higher peak troponin (6.42±1.03 vs 4.41±0.28; P=0.004), but less likely to undergo coronary angiography (54.1% vs 66.8%; P=0.03) .Patients with electrocardiographic LVH had similar in-hospital mortality (5.4% vs 3.6%, P=0.5) and heart failure/ pulmonary edema (2.7% vs 2.07%, P=0.6) compared to patients without LVH. CONCLUSION: The present study showed that among the patients with first NSTEMI, electrocardiographic LVH was not associated with increased in-hospital adverse events.
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Bakhtiari et al. (2019) conducted a cohort in First Non-ST segment elevation myocardial infarction (NSTEMI) (n=460). Electrocardiographic left ventricular hypertrophy (LVH) vs. No LVH was evaluated on In-hospital mortality (p=0.5). Electrocardiographic left ventricular hypertrophy was not associated with increased in-hospital mortality (5.4% vs 3.6%) or adverse events in patients with first NSTEMI.
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