What does this research mean for the field?

Cardiac computed tomography feature tracking (CCT-FT) demonstrates strong agreement with cardiac magnetic resonance feature tracking (CMR-FT) for global circumferential strain, providing a feasible alternative for myocardial strain assessment. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the feasibility and agreement of feature tracking cardiac computed tomography (CCT) compared to cardiac magnetic resonance (CMR) for assessing left ventricular global and regional myocardial strain.

July 29, 2025La radiologia medicaOpen Access

A comparative analysis of myocardial strain and strain rate in cardiac computed tomography and magnetic resonance feature tracking

Q: What are the key findings of this study?

Cardiac computed tomography feature tracking demonstrated strong agreement with cardiac magnetic resonance feature tracking for global circumferential strain (ICC 0.88), providing a feasible alternative for myocardial strain assessment.

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Patients referred for cardiac imaging (n=15). Intervention: Cardiac computed tomography feature tracking (CCT-FT) vs. Cardiac magnetic resonance feature tracking (CMR-FT). Primary outcome: Agreement of global circumferential strain in myocardium (ICC 0.88, 95% CI 0.63-0.96, p=<0.001).

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Key result

CCT feature tracking demonstrates strong agreement with CMR for assessing global circumferential strain.

ICC 0.88
95% CI 0.63-0.96
P<0.001
n=15

Why the study?

The feasibility of feature tracking CCT-derived LV global and regional strain and its agreement with feature tracking CMR-derived measurements had not been established.

Does cardiac computed tomography feature tracking (CCT-FT) agree with cardiac magnetic resonance feature tracking (CMR-FT) in assessing left ventricular global and regional strain in adult patients?

Population

15 adult patients

Comparison

Feature tracking CCT vs feature tracking CMR

Design

Comparative imaging study

Authors

IDIrene Del‐CantoUniversitat de València MLMaría P. López‐LereuCardiac Imaging JMJosé V. MonmeneuCardiac Imaging

Discussion

Member takes

Implication

May support CCT-FT for global strain when CMR unavailable; leaves open validation in prospective outcome studies.

Key Points

To evaluate the feasibility and agreement of feature tracking cardiac computed tomography (CCT) compared to cardiac magnetic resonance (CMR) for assessing left ventricular global and regional myocardial strain.
Assessed 15 adult patients (50% women, mean age: 65 ± 9 years) undergoing both CMR and CCT imaging.
Calculated left ventricular global and segmental circumferential and longitudinal strain and strain rate via feature tracking (FT) technology on both modalities.
Evaluated inter-modality agreement and reproducibility using Bland–Altman analysis and intraclass correlation coefficients (ICC).
Feature tracking strain and strain rate analyses were successfully completed in 100% of participants across both CCT and CMR modalities.
Inter-technique agreement was strong for global circumferential strain (ICC > 0.75) and moderate for other global strain parameters (ICC > 0.50).
Bland–Altman analysis demonstrated that CCT-FT yielded lower values than CMR-FT for left ventricular global longitudinal strain (mean difference: 5.32%) and strain rate (mean difference: 0.71 s⁻¹).

Study Design

Type

Observational (n=15)

Multicenter

Structured PICO

Does cardiac computed tomography feature tracking (CCT-FT) agree with cardiac magnetic resonance feature tracking (CMR-FT) in assessing left ventricular global and regional strain in adult patients?

Population

15 adult patients (50% women, mean age: 65 ± 9 years) referred for both CMR and helical CCT studies within a time interval of less than 6 months. Exclusion criteria: recurrent MIs, severe clinical instability or cardiac surgery, contraindication to CMR, and insufficient CMR study quality.

Intervention

Cardiac computed tomography feature tracking (CCT-FT) for assessing left ventricular global and segmental circumferential and longitudinal strain and strain rate

Comparator

Cardiac magnetic resonance feature tracking (CMR-FT)

Outcome

Agreement between CCT-FT and CMR-FT measurements of LV global and segmental circumferential and longitudinal strain and strain rate (evaluated using Bland–Altman analysis and intraclass correlation coefficient)surrogate

Main Result

Effect estimate: ICC 0.88 (95% CI 0.63-0.96)

p-value: p=<0.001

Cardiac computed tomography feature tracking is a feasible alternative to cardiac magnetic resonance for assessing myocardial strain, showing strong agreement particularly for global circumferential strain.

Limitations

Small sample size
Retrospective design from a single institution
Greater radiation exposure compared to typical CT protocols due to retrospective ECG-gated acquisition
Standard values for CCT-FT derived strain are not established

Cite This Study

Del‐Canto et al. (2025) conducted an observational in Patients referred for cardiac imaging (n=15). Cardiac computed tomography feature tracking (CCT-FT) vs. Cardiac magnetic resonance feature tracking (CMR-FT) was evaluated on Agreement of global circumferential strain in myocardium (ICC 0.88, 95% CI 0.63-0.96, p=<0.001). Cardiac computed tomography feature tracking demonstrated strong agreement with cardiac magnetic resonance feature tracking for global circumferential strain (ICC 0.88), providing a feasible alternative for myocardial strain assessment.

synapsesocial.com/papers/6a1c0f5c26cb5670aa9d50dc https://doi.org/10.1007/s11547-025-02060-5

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A comparative analysis of myocardial strain and strain rate in cardiac computed tomography and magnetic resonance feature tracking

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

A comparative analysis of myocardial strain and strain rate in cardiac computed tomography and magnetic resonance feature tracking

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Also Consider

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