Key result
Incremental atrial burst pacing and double atrial extrastimulation revealed multiple anterograde AV nodal physiology in an additional 32% of patients compared to conventional single extrastimulation.
Why the study?
Does the use of A1A1 and A1A2A3 pacing protocols improve the characterization of multiple anterograde AV nodal physiology in patients with AVNRT compared to A1A2 alone?
Observational (n=223)
Does the use of A1A1 and A1A2A3 pacing protocols improve the characterization of multiple anterograde AV nodal physiology in patients with AVNRT compared to A1A2 alone?
The combination of A1A2, A1A1, and A1A2A3 pacing protocols is required to fully elucidate AV nodal physiology and confirm successful ablation in AVNRT.
May enhance AV nodal pathway detection in AVNRT; hypothesis-generating for routine protocol adoption before changing practice.
This article describes the additional use of incremental atrial burst pacing (A1A1) and double atrial extrastimulation with a predefined fast pathway conducted A2 (A1A2A3), rather than single atrial extrastimulation (A1A2) only, to characterize typical atrioventricular nodal reentrant tachycardia (AVNRT). The authors noted an additional 32% of patients had multiple anterograde AV nodal physiology demonstrated when A1A1 or A1A2A3 protocols were deployed compared to more conventional A1A2 protocols. The A2H2max (449 +/- 147 vs 339 +/- 94 ms) and A3H3max (481 +/- 120 vs 389 +/- 85 ms) were higher in 31 patients where multiple jumps in the AV nodal conduction curve were obtained (group 1) compared to 192 patients where only single jump was obtained (group 2) (both P < 0.01). Postablation, the degree of reduction of A2H2max (49%) and A3H3max (50%) in group 1 was greater than in group 2 (38% and 42%, respectively, P < 0.05). In seven of group 1 patients in whom A1A2A3 stimulation was required to reveal multiple jumps, the A2H2max remained unchanged after ablation (237 +/- 89 vs 214 +/- 59, P > 0.05). A3H3max was the only parameter that shortened significantly after ablation. Generally, successful ablation resulted in loss of multiple discontinuities in A1A1/A1H1 or A2A3/A3H3 curves. In conclusion, a combination of A1A2, A1A1, and A1A2A3 are required to fully elucidate AVNRT. Significant shortening of AHmax or loss of multiple jumps after ablation indicates successful elimination of AVNRT in these patients.
No takes yet. Share an insight, caveat, or question.
Kuo et al. (2003) conducted an observational in Atrioventricular nodal reentrant tachycardia (AVNRT) (n=223). Incremental atrial burst pacing (A1A1) and double atrial extrastimulation (A1A2A3) vs. Single atrial extrastimulation (A1A2) was evaluated on Degree of reduction of A2H2max postablation (p=<0.05). Incremental atrial burst pacing and double atrial extrastimulation revealed multiple anterograde AV nodal physiology in an additional 32% of patients compared to conventional single extrastimulation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: