Key result
Simultaneous endocardial and epicardial mapping in patients with long-lasting persistent atrial fibrillation revealed low frequency and amplitude activity that inversely correlated with MRI-detected fibrosis.
Why the study?
The study was conducted to perform simultaneous endocardial and epicardial mapping of the left atrium and evaluate the results in patients with long-lasting persistent AF.
Observational (n=13)
No
Answers are grounded in this paper and cite their sources.
Simultaneous endocardial and epicardial mapping reveals low frequency and amplitude activity in long-persistent AF, which inversely correlates with the degree of atrial fibrosis.
Objective. Perform simultaneous endocardial and epicardial mapping of the left atrium (LA) in patients with long-lasting persistent atrial fibrillation (AF) and evaluate the results. Material and methods. Based on the Bakoulev National Medical Research Center for Cardiovascular Surgery used sphe-rical 64-pole and plate 64-pole electrodes to perform simultaneous endocardial and epicardial mapping of the LA in 13 patients with long-lasting persistent AF. The system “Biotok” (Russia) was used for mapping. A spherical electrode was inserted into the LA through the right superior pulmonary vein to construct the volume and map the LA from the endocardial surface. A plate electrode was alternately moved across all regions of the LA to construct the volume and map the epicardial surface. At the same time, elec-trograms were obtained, with the help of which the frequency spectrum and amplitude activity in each region of the LA were analyzed. Based on the results obtained. patients long-lasting persistent form of AF, the frequency spectrum and amplitude activity were low: on average, 3.06±0.79 Hz and 0.29±0.14 mV for the endocardial surface of the LA, 4.1±1.06 Hz and 4.13±2.32 mV for the epicardial surface of the LA, respectively. The correlation coefficient (r), equal to 0.99 for the endocardial surface of the LA and r=0.51 for the epicardial surface of the LA, obtained by analyzing the relationship of the frequency spectrum with the amplitude activity of the same regions of the LA. The correlation analysis of the frequency spectrum and amplitude activity from the endocardial and epicardial surfaces of the LA with the data of fibrous changes of the LA obtained during magnetic resonance imag-ing (MRI) was performed. At the same time, negative values of the correlation coefficient were revealed. epicardial mapping the LA developed. correlation frequency amplitude different regions the LA the long-lasting persistent form AF data of fibrous changes of the LA determined during MRI. It is shown that in the long-lasting persistent form of AF in the LA, the frequency and amplitude activity have low values.
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Bockeriа et al. (2019) conducted an observational in Long-lasting persistent atrial fibrillation (n=13). Simultaneous endocardial and epicardial mapping was evaluated on Frequency spectrum and amplitude activity of the left atrium. Simultaneous endocardial and epicardial mapping in patients with long-lasting persistent atrial fibrillation revealed low frequency and amplitude activity that inversely correlated with MRI-detected fibrosis.
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