Key result
Hypertensive women with CAD and prior MI or revascularization were at higher risk for death, nonfatal MI, and nonfatal stroke, and less likely to achieve BP control despite aggressive therapy.
Why the study?
Are hypertensive women with CAD and prior MI or revascularization at higher risk for adverse cardiovascular events and poorer blood pressure control?
Cohort
Yes
Are hypertensive women with CAD and prior MI or revascularization at higher risk for adverse cardiovascular events and poorer blood pressure control?
Hypertensive women with severe CAD (prior MI or revascularization) have higher cardiovascular risk and poorer blood pressure control, highlighting the need for further investigation into optimal BP targets for this high-risk population.
Should not yet alter BP targets; leaves open optimal control thresholds for hypertensive women with CAD and prior events.
In a prospective, multinational cohort of hypertensive women with CAD, those with prior MI or revascularization comprised a group at higher risk for death, nonfatal MI, and nonfatal stroke, and were less likely to have their BP controlled, despite more aggressive therapy. The feasibility and benefit of reducing BP to <130/80 mmHg in women, particularly with more severe CAD, warrant further investigation.
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Sava et al. (2019) conducted a cohort in Hypertensive women with coronary artery disease. Prior MI or revascularization vs. No prior MI or revascularization was evaluated on Death, nonfatal MI, and nonfatal stroke; blood pressure control. Hypertensive women with CAD and prior MI or revascularization were at higher risk for death, nonfatal MI, and nonfatal stroke, and less likely to achieve BP control despite aggressive therapy.
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