Key result
In healthy young individuals with a normal body mass index, increased BMI was independently associated with increased maximum P-wave duration (SC +0.112), increased P-wave balance, a leftward shift of the heart axis, and decreased Sokolow-Lyon voltage.
Why the study?
The association between BMI and electrocardiographic parameters in healthy young individuals with a normal body mass index is unknown.
Does body mass index correlate with electrocardiographic alterations in healthy young individuals with a normal BMI?
Cross-Sectional (n=1,290)
No
Does body mass index correlate with electrocardiographic alterations in healthy young individuals with a normal BMI?
Effect estimate: SC +0.112
p-value: p=<0.001
Even within the normal range, an increased BMI in healthy young individuals is independently associated with discrete electrocardiographic alterations such as increased P-wave duration and a leftward shift of the heart axis.
Even normal-range BMI links to ECG changes in young adults; hypothesis-generating for prospective arrhythmia risk studies.
INTRODUCTION: ) is unknown. The aim of this study was to evaluate the association between BMI and electrocardiographic parameters. METHODS: ) were divided into BMI quartiles analysis and a backward multivariate regression analysis with a normal BMI as a continuous variable was performed. RESULTS: Mean age was 22.7 ± 3.0 years, mean BMI was 22.0, and 73.4% were male. There were significant differences between the BMI quartiles in terms of maximum P-wave duration, P-wave balance, total P-wave area in lead V1, PR-interval duration, and heart axis. In the multivariate model maximum P-wave duration (standardised coefficient (SC) = +0.112, P < 0.001), P-wave balance in lead V1 (SC = +0.072, P < 0.001), heart axis (SC = -0.164, P < 0.001), and Sokolow-Lyon voltage (SC = -0.097, P < 0.001) were independently associated with BMI. CONCLUSION: Increased BMI was related with discrete electrocardiographic alterations including an increased P-wave duration, increased P-wave balance, a leftward shift of the heart axis, and decreased Sokolow-Lyon voltage on a standard twelve lead electrocardiogram in healthy young individuals with a normal BMI.
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Hassing et al. (2019) conducted a cross-sectional in Healthy individuals with normal body mass index (n=1,290). Body mass index (BMI) was evaluated on Maximum P-wave duration (SC +0.112, p=<0.001). In healthy young individuals with a normal body mass index, increased BMI was independently associated with increased maximum P-wave duration (SC +0.112), increased P-wave balance, a leftward shift of the heart axis, and decreased Sokolow-Lyon voltage.
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