Multi-modality image registration by maximization of mutual information

Mutual information of image intensities has been proposed as a new matching criterion for automated multi-modality image registration. In this paper the authors give experimental evidence of the power and the generality of the mutual information criterion by showing results for various applications involving CT, MR and PET images. The authors' results illustrate the large applicability of the approach and demonstrate its high suitability for routine use in clinical practice.