Key result
Microalbuminuria was significantly associated with left ventricular hypertrophy in non-diabetic hypertensive patients, occurring in 80% of those with microalbuminuria compared to 13.6% of those with normal urine protein.
Cross-Sectional (n=100)
Single-blind
No
Microalbuminuria is significantly associated with left ventricular hypertrophy in non-diabetic hypertensive patients, supporting its use as an early screening marker for target organ damage.
Should not yet change LVH screening practice in non-diabetic hypertension; hypothesis-generating for microalbuminuria as target-organ marker.
Microalbuminuria is an early manifestation of kidney damage and independently predicts cardiovascular disease (CVD). Microalbuminuria is considered a reliable indicator of endothelial dysfunction. Endothelial dysfunction is considered an early step of atherosclerosis and represents increased risk of cardiovascular events. Left ventricular hypertrophy (LVH) is also an early marker of cardiac manifestation of target organ damage among hypertensive patients. This study aimed at determining microalbuminuria as an early predictor of left ventricular hypertrophy in non-diabetic hypertensives.
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Kinagi et al. (2015) conducted a cross-sectional in Essential hypertension (non-diabetic) (n=100). Microalbuminuria vs. Normoalbuminuria was evaluated on Abnormal cardiac geometry (Left ventricular hypertrophy) (p=<0.0001). Microalbuminuria was significantly associated with left ventricular hypertrophy in non-diabetic hypertensive patients, occurring in 80% of those with microalbuminuria compared to 13.6% of those with normal urine protein.
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