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A single-blind study compared the clinical efficacy of biperiden hydrochloride (Akineton, Abbott) and benzhexol (Artane, Lederle) in the treatment of neuroleptic-induced Parkinsonism. Both drugs were highly effective and all patients responded favourably to medication. No significant difference was observed between the two treatment groups when individual symptoms were examined.
Ralph V. Magnus (Mon,) studied this question.