Key result
Coronary CT angiography demonstrated that 23.3% of patients with hypertrophic cardiomyopathy had coexistent obstructive coronary artery disease and 42.7% had myocardial bridging.
Observational (n=150)
No
Supports CTA screening for CAD and bridging in HCM; extends prevalence data with RCT-level evidence.
Hypertrophic cardiomyopathy (HCM) is a complex and relatively common genetic cardiac disease with an estimated prevalence of 0.2% (1). Frequently, patients with HCM have chest pain suggestive of angina pectoris, and the electrocardiogram (ECG) can resemble that of a myocardial infarction (MI) in the absence of coronary artery disease (CAD) (2, 3). However, adult patients with HCM may also develop atherosclerotic CAD, and patients with HCM and coexistent CAD have an increased rate of morbidity compared to patients with HCM without CAD (4, 5). Therefore, early detection of coexistent CAD in HCM is of high importance. Myocardial bridging (MB) is more commonly associated with Coexistent Coronary Artery Disease or Myocardial Bridging in Patients with Hypertrophic Cardiomyopathy Using Coronary CT Angiography 비후성 심근증을 가진 성인 환자에서 동반되는 관상동맥질환과 심근교락: 다중검출기 심장 CT를 통한 연구
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Lee et al. (2015) conducted an observational in Hypertrophic cardiomyopathy (HCM) (n=150). Coronary CT angiography (CCTA) vs. Invasive coronary angiography (ICA) was evaluated on Prevalence of obstructive coronary artery disease (>50% luminal reduction). Coronary CT angiography demonstrated that 23.3% of patients with hypertrophic cardiomyopathy had coexistent obstructive coronary artery disease and 42.7% had myocardial bridging.
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