Key result
Conducted vasodilation, driven by electrical signaling through gap junctions along the endothelium, allows local vasodilation to ascend into feed arteries to increase total oxygen supply.
Design
Review
Authors
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May inform microvascular impairment in aging and disease; leaves open targeted interventions for exercise capacity.
This review highlights the critical role of conducted vasodilation via endothelial gap junctions in regulating microcirculatory blood flow, which is essential for exercise capacity and impaired in aging and disease.
Bagher et al. (2010) conducted a review in Microcirculation blood flow regulation. Conducted vasodilation was evaluated. Conducted vasodilation, driven by electrical signaling through gap junctions along the endothelium, allows local vasodilation to ascend into feed arteries to increase total oxygen supply.
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