Why the study?
To determine if critically ill patients experience cardiac atrophy quantifiable as a loss of left ventricular mass detected by echocardiography.
Does critical illness with prolonged ICU stay (≥ 5 days) lead to cardiac atrophy as measured by a loss of left ventricular mass?
Cohort (n=42)
No
Does critical illness with prolonged ICU stay (≥ 5 days) lead to cardiac atrophy as measured by a loss of left ventricular mass?
Critically ill adults with prolonged ICU stays experience a significant reduction in left ventricular mass without changes in relative wall thickness, suggesting the development of cardiac atrophy.
Answers are grounded in this paper and cite their sources.
May indicate cardiac atrophy in prolonged critical illness; hypothesis-generating for functional impact and interventions.
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Kumaresan et al. (2022) conducted a cohort in Critical illness (n=42). Critical illness (ICU admission) vs. Baseline (admission) was evaluated on Change in left ventricular mass (LVM) (Mean difference -21.30 g, 95% CI -41.85 to -0.74, p=0.04).
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