The influence of hyperthermia on the survival of irradiated oxic and hypoxic HeLa cells was determined. A significant reduction in OER was obtained for irradiated cells subsequently cultivated at 42-degrees C for two hours compared to irradiated cells cultivated at 37-degrees C. These results suggest that heating irradiated hypoxic cells is an effective means of reducing the oxygen dependence factor in radiation effects.
No takes yet. Share an insight, caveat, or question.
Kim et al. (1975) studied this question.