Key result
Reperfusion haemorrhage following AMI independently predicted adverse ventricular remodelling (OR 1.6, p=0.001) and prolonged filtered QRS duration (OR 1.176, p=0.020) at 3 months.
Why the study?
Does myocardial haemorrhage detected by CMR predict adverse ventricular remodelling and markers of late arrhythmic risk in patients with first ST-elevation AMI treated with PPCI?
Cohort (n=48)
Does myocardial haemorrhage detected by CMR predict adverse ventricular remodelling and markers of late arrhythmic risk in patients with first ST-elevation AMI treated with PPCI?
Effect estimate: OR 1.6
p-value: p=0.001
Reperfusion haemorrhage detected by CMR after AMI is an independent predictor of adverse ventricular remodelling and prolonged fQRS duration, a marker of arrhythmic risk.
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May support CMR haemorrhage assessment for post-AMI risk stratification; leaves open prospective validation and therapeutic targeting.
Mather et al. (2010) conducted a cohort in Acute myocardial infarction (n=48). Myocardial haemorrhage vs. Non-haemorrhagic MI was evaluated on Adverse remodelling defined as increased LVESV on follow-up (OR 1.6, p=0.001). Reperfusion haemorrhage following AMI independently predicted adverse ventricular remodelling (OR 1.6, p=0.001) and prolonged filtered QRS duration (OR 1.176, p=0.020) at 3 months.
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