Association of sleep characteristics with atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis
Key result
Longer duration of slow wave sleep was associated with significantly lower odds of prevalent atrial fibrillation (OR 0.66; 95% CI 0.5 to 0.89; p=0.01), independent of apnoea hypopnoea index.
Why the study?
Are sleep characteristics such as sleep disordered breathing and sleep quality associated with prevalent atrial fibrillation in a multiethnic population?
Population
2048 participants from the Multi-Ethnic Study of Atherosclerosis (MESA) who underwent polysomnography
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May support sleep optimization research in AF; leaves open causality and clinical utility pending prospective data.
Study Design
Type
Cross-Sectional (n=2,048)
Structured PICO
Are sleep characteristics such as sleep disordered breathing and sleep quality associated with prevalent atrial fibrillation in a multiethnic population?
P
Population
2048 participants from the Multi-Ethnic Study of Atherosclerosis (MESA) who underwent polysomnography
I
Intervention
Sleep characteristics (apnea hypopnea index, slow wave sleep duration, sleep efficiency, arousal index, sleep duration)
O
Outcome
Prevalent atrial fibrillation (AF) defined by diagnosis codes, study electrocardiography and sleep studyhard clinical
Main Result
Effect estimate: OR 0.66 (95% CI 0.5 to 0.89)
p-value: p=0.01
Poor sleep quality, specifically reduced slow wave sleep time, is associated with prevalent atrial fibrillation independently of sleep apnea severity.
Cite This Study
Kwon et al. (2015) conducted a cross-sectional in Atrial fibrillation (n=2,048). Sleep characteristics (apnoea hypopnoea index, slow wave sleep duration) was evaluated on Prevalent atrial fibrillation (OR 0.66, 95% CI 0.5 to 0.89, p=0.01). Longer duration of slow wave sleep was associated with significantly lower odds of prevalent atrial fibrillation (OR 0.66; 95% CI 0.5 to 0.89; p=0.01), independent of apnoea hypopnoea index.