Why the study?
Does coronary angioplasty prevent recurrence of atrial fibrillation in a patient with exercise-induced paroxysmal AF and LAD stenosis?
Does coronary angioplasty prevent recurrence of atrial fibrillation in a patient with exercise-induced paroxysmal AF and LAD stenosis?
Coronary ischemia due to LAD stenosis can be a treatable cause of exercise-induced paroxysmal atrial fibrillation, resolvable with coronary angioplasty.
Coronary angioplasty may resolve exercise-induced paroxysmal AF linked to LAD stenosis; hypothesis-generating and requires prospective confirmation.
We present a patient with exercise-induced paroxysmal atrial fibrillation who was eventually scheduled for a Cox-maze operation due to persistence of his complaints of fatigue, impaired exercise tolerance, and predominantly exercise-related irregular palpitations despite treatment with several antiarrhythmic drugs. A preoperative exercise stress test without antiarrhythmic or negative chronotropic drugs, however, showed clear evidence of myocardial ischemia. After coronary angioplasty of a significant stenosis in the left anterior descending artery, there was no recurrence of atrial fibrillation during a follow-up of 7 months.
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Schoonderwoerd et al. (1999) studied this question.
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