Key result
Small extracellular vesicles mediate immune regulation of tissue remodeling and angiogenesis after myocardial infarction, presenting a promising cell-free therapeutic strategy for cardiac repair.
Why the study?
Clinical trials of cell-based therapies for myocardial infarction have shown variable results, prompting interest in small extracellular vesicles as a cell-free therapeutic strategy to regulate tissue remodeling and angiogenesis.
Design
Review
Authors
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Should not yet change post-MI practice; leaves open cell-free vesicle therapy as hypothesis-generating.
This review summarizes the role of immune cell-derived small extracellular vesicles in regulating angiogenesis and tissue remodeling after myocardial infarction, proposing them as a potential cell-free therapy.
Sánchez‐Alonso et al. (2018) conducted a review in Myocardial Infarction. Small extracellular vesicles (EVs) was evaluated. Small extracellular vesicles mediate immune regulation of tissue remodeling and angiogenesis after myocardial infarction, presenting a promising cell-free therapeutic strategy for cardiac repair.
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