Depression, Diabetes, and Glycemic Control in an American Indian Community
Key result
Depression in Pima Indians with diabetes was associated with significantly higher mean glycosylated hemoglobin levels compared to those without depression (9.0% vs. 8.4%, p=0.02).
Why the study?
Is depression associated with diabetes prevalence and worse glycemic control in Pima Indians?
Population
2,902 adults from the Gila River Indian Community in Arizona, including 1,121 with diabetes and 1,781…
Comparison
Depression vs No depression
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Depression linked to worse control in diabetic Pima Indians; hypothesis-generating and requires prospective validation before guiding care.
Study Design
Type
Cross-Sectional (n=2,902)
Multicenter
No
Structured PICO
Is depression associated with diabetes prevalence and worse glycemic control in Pima Indians?
P
Population
2,902 adults (aged ≥18 years) from the Gila River Indian Community in Arizona, including 1,121 with diabetes and 1,781 without diabetes.
I
Intervention
Depression (evaluated with the depression module of the Patient Health Questionnaire using DSM-IV criteria)
C
Comparator
No depression
O
Outcome
Prevalence of depression and mean glycosylated hemoglobin levelssurrogate
Main Result
Absolute Event Rate: 9% vs 8.4%
p-value: p=0.02
Depression is associated with worse glycemic control among Pima Indians with diabetes, suggesting that identifying and treating depression may help reduce the risk of diabetic complications.
Cite This Study
Sahota et al. (2008) conducted a cross-sectional in Diabetes (n=2,902). Depression vs. No depression was evaluated on Mean glycosylated hemoglobin levels among participants with diabetes (p=0.02). Depression in Pima Indians with diabetes was associated with significantly higher mean glycosylated hemoglobin levels compared to those without depression (9.0% vs. 8.4%, p=0.02).