Key result
Early diagnostics of kidney damage in essential hypertension relies on laboratory methods (GFR, microalbuminuria) and Doppler assessment of intrarenal hemodynamics to guide management.
This review discusses the mechanisms of renal vessel remodeling and the utility of laboratory and Doppler methods for early detection of kidney damage in essential hypertension.
Supports lab and Doppler monitoring for early renal damage in hypertension; leaves open prospective outcome trials.
We review main issues of early diagnostics of kidney damage in patients with essential hypertension. The remodeling of renal vessels and the underlying mechanisms are discussed. The evidence-based data are reviewed to substantiate the use of laboratory methods for the kidney damage diagnostics (calculation of glomerular fltration rate and microalbuminuria). We discuss the role of Doppler methods in the assessment of intrarenal hemodynamics (the resistance index and blood flow acceleration time) for timely detection of changes in renal vessels and the choice of management strategy.
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Мельникова et al. (2019) conducted a review in essential arterial hypertension. Early diagnostics of kidney damage (laboratory and Doppler methods) was evaluated. Early diagnostics of kidney damage in essential hypertension relies on laboratory methods (GFR, microalbuminuria) and Doppler assessment of intrarenal hemodynamics to guide management.
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