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A 68-year-old man presents with newly diagnosed prostate cancer. Over the past 3 years, his prostate-specific antigen level has slowly and steadily increased. His digital rectal examination is normal, the estimated prostate volume is 48 ml, and a needle-biopsy specimen reveals an adenocarcinoma with a Gleason score of 6 involving 10% of 1 of the 12 cores. He otherwise is well. How should his case be managed?
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Walsh et al. (2007) studied this question.
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