Key result
Flight attendants (N=26) with remote in-cabin secondhand smoke exposure exhibited preclinical signs of accelerated vascular aging, including abnormal pulse pressure and flow-mediated dilation.
Why the study?
To determine whether early vascular aging may be present in flight attendants with remote in-cabin secondhand smoke exposure.
Does remote in-cabin secondhand smoke exposure accelerate vascular aging in flight attendants?
Observational (n=26)
Does remote in-cabin secondhand smoke exposure accelerate vascular aging in flight attendants?
Remote occupational secondhand smoke exposure in flight attendants is associated with preclinical signs of accelerated vascular aging.
Should not change practice; hypothesis-generating for remote SHS vascular effects in occupational cohorts.
OBJECTIVE: To determine whether early vascular aging may be present in flight attendants with remote in-cabin secondhand smoke (SHS) exposure. METHODS: Twenty-six flight attendants with a history of in-cabin SHS exposure prior to the airline smoking bans were recruited. Pulse wave analysis, peripheral arterial tonometry, and brachial artery reactivity testing evaluated their arterial compliance and endothelial function. RESULTS: Flight attendants with remote in-cabin SHS exposure have normal blood pressure, pulse wave velocity, and reactive hyperemia index, but abnormal pulse pressure, augmentation index, flow-mediated dilation, and hyperemic mean flow ratio. CONCLUSION: These preliminary findings suggest that flight attendants with remote in-cabin SHS exposure have preclinical signs of accelerated vascular aging and raise new questions about the relationship between remote SHS exposure and vascular health.
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Wei et al. (2018) conducted an observational in Occupational secondhand smoke exposure (n=26). Remote in-cabin secondhand smoke exposure was evaluated on Arterial compliance and endothelial function. Flight attendants (N=26) with remote in-cabin secondhand smoke exposure exhibited preclinical signs of accelerated vascular aging, including abnormal pulse pressure and flow-mediated dilation.
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