Key result
The ability to record transmembrane potentials of cardiac muscle using microelectrodes brought about a rapid increase in understanding the basis for normal and abnormal cardiac electrical activity.
The introduction of the microelectrode revolutionized cardiac electrophysiology by allowing the recording of transmembrane potentials and understanding the ionic basis of cardiac electrical activity.
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Microelectrode recordings established ionic mechanisms of excitability; leaves open how best to integrate these insights with modern genomic and device therapies.
Brian F. Hoffman (2002) conducted an editorial in Cardiac electrophysiology. Microelectrode was evaluated. The ability to record transmembrane potentials of cardiac muscle using microelectrodes brought about a rapid increase in understanding the basis for normal and abnormal cardiac electrical activity.
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