Key result
Direct-to-Lab workflow linked to ~20 minutes faster FMC-to-balloon time in stable STEMI vs standard triage.
Why the study?
Reducing total ischemic time makes first-medical-contact-to-balloon time a key metric in STEMI, motivating a Direct to Lab workflow to improve times for patients presenting via EMS.
Does a 'Direct to Lab' workflow reduce door-to-balloon and first-medical-contact-to-balloon times in hemodynamically stable EMS STEMI patients?
Observational (n=30)
No
Does a 'Direct to Lab' workflow reduce door-to-balloon and first-medical-contact-to-balloon times in hemodynamically stable EMS STEMI patients?
Absolute Event Rate: 59% vs 79%
p-value: p=0.0010
Implementing a 'Direct to Lab' workflow for stable EMS STEMI patients significantly reduces ED, door-to-balloon, and first-medical-contact-to-balloon times without increasing procedural complications.
Background Rapid treatment of ST-elevation myocardial infarction (STEMI) patients with primary percutaneous coronary intervention (PCI) significantly reduces morbidity and mortality rates. Recent studies emphasize the importance of reducing total ischemic time, making first-medical-contact-to-balloon (FMCTB) time a key performance indicator. To improve FMCTB times in patients brought to the Emergency Department (ED) by Emergency Medical Services (EMS), we implemented a "Direct to Lab" (DTL) workflow during the following conditions: weekday daytime hours, when the lab is fully staffed, and for hemodynamically stable STEMI patients presenting via EMS. Methods We performed a pre/post analysis following the implementation of a pilot workflow for EMS STEMI patients to be rapidly triaged to the cardiac catheterization lab as compared to those patients who underwent the standard workflow before program implementation at a 225-bed community hospital in a suburban setting in Maryland, USA. The hospital's STEMI database was queried from 2/1/2021 through 3/1/2024, including all EMS STEMI alert activations during the study period. Cases were excluded if the patient arrived after program operating hours, declined PCI, or if clinical circumstances (such as cardiac arrest or the need for other resuscitative or diagnostic interventions) necessitated additional ED stabilization before PCI. Results A total of 30 patients met the inclusion criteria. The analysis revealed significantly reduced ED, door-to-balloon (DTB), and FMCTB times for patients under the "Direct to Lab" workflow, including a total ED time of 8.4 minutes faster, an average DTB time of 19.6 minutes faster, and an average FMCTB time of 24.3 minutes faster than those triaged via the standard workflow. Complication rates were similar among both groups. The most common reason that stable patients were not taken directly to the lab was the need for further clinical evaluation before cardiac catheterization or the lab not being immediately available. Conclusion In this pilot single-center analysis, STEMI patients who were expeditiously triaged "Direct to Lab" experienced significantly lower total ED, DTB, and FMCTB times with no difference in procedural complications. This study highlights the patient-centered benefits of a robust collaboration between EMS, ED, and Interventional Cardiology teams.
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Levy et al. (2024) conducted an observational in ST-elevation myocardial infarction (STEMI) (n=30). Direct to Lab (DTL) workflow vs. Standard ED triage workflow was evaluated on Median first-medical-contact-to-balloon (FMC2B) time in minutes (p=0.0010). The Direct to Lab workflow significantly reduced median first-medical-contact-to-balloon time to 59.0 minutes compared to 79.0 minutes with standard triage for hemodynamically stable STEMI patients.
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