Key result
Multidisciplinary management and strict BP control improve pregnancy outcomes in thoracic aortic disease.
Why the study?
Thoracic aortic disease poses substantial risks during pregnancy, particularly for women with genetic conditions such as Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome.
This review emphasizes the critical need for preconception counseling, multidisciplinary cardio-obstetrics care, and strict medical management to mitigate the high risks of thoracic aortic disease during pregnancy.
May support preconception counseling and multidisciplinary care in thoracic aortic disease; leaves open need for prospective trials to guide practice.
Thoracic aortic disease (TAD) poses substantial risks during pregnancy, particularly for women with genetic conditions such as Marfan syndrome, Loeys-Dietz syndrome, and vascular Ehlers-Danlos syndrome. This review examines the epidemiology, risk assessment, and management of TAD in pregnancy. Preconception counseling is vital considering the hereditary nature of TAD and potential pregnancy-related complications. Genetic testing and imaging surveillance aid in risk assessment. Medical management, including beta-blockade and strict blood pressure control, is essential throughout pregnancy. Surgical interventions may be necessary in certain cases. A multidisciplinary approach involving cardiologists, obstetricians, cardiac surgeons, anesthesiologists, and other specialists with expertise in cardio-obstetrics is essential for optimal outcomes. Patient education and shared decision-making play vital roles in navigating the complexities of TAD in pregnancy and improving maternal and neonatal outcomes.
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Duarte et al. (2024) conducted a review in Thoracic Aortic Disease in pregnancy. Thoracic aortic disease poses substantial risks during pregnancy, necessitating preconception counseling, strict blood pressure control, and a multidisciplinary approach to improve outcomes.
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