Why the study?
Do myocardial exchanges of glutamate, alanine, and citrate differ between patients with coronary artery disease and controls during rest, atrial pacing, and recovery?
Population
17 patients with coronary artery disease and 7 control subjects
Comparison
Measurement of myocardial exchanges of plasma… vs Control subjects without coronary artery disease
Design
Case-control
Authors
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Myocardial exchanges may mark ischemia severity in CAD; leaves open validation as adjunctive biomarkers beyond lactate.
Do myocardial exchanges of glutamate, alanine, and citrate differ between patients with coronary artery disease and controls during rest, atrial pacing, and recovery?
Measurement of myocardial exchanges of glutamate, alanine, and citrate may serve as a sensitive biochemical test for assessing myocardial ischemia in humans.
Thomassen et al. (1983) studied this question.
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