Wide or unselected use of high sensitivity cardiac troponin testing frequently yields elevated concentrations reflecting myocardial injury rather than myocardial infarction.
Cohort
Does patient selection influence the positive predictive value of high sensitivity cardiac troponin testing for the diagnosis of myocardial infarction?
Patient selection for high sensitivity cardiac troponin testing markedly influences its positive predictive value for diagnosing myocardial infarction.
When high sensitivity cardiac troponin testing is performed widely or without previous clinical assessment, elevated troponin concentrations are common and predominantly reflect myocardial injury rather than myocardial infarction. These observations highlight how selection of patients for cardiac troponin testing varies across healthcare settings and markedly influences the positive predictive value for a diagnosis of myocardial infarction.
Shah et al. (Tue,) conducted a cohort in myocardial infarction. high sensitivity cardiac troponin testing was evaluated on diagnosis of myocardial infarction. Wide or unselected use of high sensitivity cardiac troponin testing frequently yields elevated concentrations reflecting myocardial injury rather than myocardial infarction.