Population
Human peripheral blood monocytes and the murine macrophage-like cell line J774
Comparison
Cyanogen bromide fragment CB67-129 of human… vs iPr2P derivatives of chymotrypsin and trypsin…
Design
Preclinical
Authors
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Thrombin fragment CB67-129 drives monocyte chemotaxis via peptide structure; leaves open its role in human vascular inflammation.
The chemotactic activity of human thrombin is localized to the CB67-129 fragment of the B chain, specifically related to its unique peptide structure rather than its carbohydrate moieties.
Bar‐Shavit et al. (1984) studied this question.
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