Key result
Signal averaged ECG maintains similar predictive accuracy for ventricular tachycardia and sudden cardiac death in Japanese populations compared to Westerners despite lower disease prevalence.
Why the study?
What is the clinical significance and what are the normal values of signal averaged ECG in the Japanese population?
What is the clinical significance and what are the normal values of signal averaged ECG in the Japanese population?
This review highlights the need to establish specific normal values for signal-averaged ECG in the Japanese population to accurately predict ventricular arrhythmias and sudden cardiac death.
Warrants caution applying Western SAECG norms to Japanese patients; leaves open prospective validation of population-specific thresholds.
Although studies show that the ventricular tachycardia and sudden cardiac deaths caused by ischemic heart diseases affect Japanese less than Westerners, predictive accuracy of the signal averaged ECG for ventricular tachycardia and sudden cardiac deaths are almost the same as the results for Westerners. The recent prognosis of ischemic heart diseases is showing improvements along with the development of re-perfusion therapy, which is changing the significance of the signal averaged ECG. Therefore a clinical use for signal averaged ECG should be discussed in cases of cardiomyopathy which cause sudden cardiac deaths and other heart diseases. So it is necessary to redetermine normal values of the signal averaged ECG parameters. In this article, the following was reviewed on the basis of our studies regarding the clinical significance of the signal averaged ECG of Japanese and normal signal averaged ECG values. (1) System and gender specific differences on signal averaged ECG of Japanese, (2) His-Purkinje system, pre-P deflection and atrial late potential on signal averaged ECG, (3) Ventricular late potentials of Japanese.
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Yukio Ozawa (1999) conducted a review in Ischemic heart disease and cardiomyopathy. Signal averaged ECG was evaluated. Signal averaged ECG maintains similar predictive accuracy for ventricular tachycardia and sudden cardiac death in Japanese populations compared to Westerners despite lower disease prevalence.
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