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The genomes of the human adenoviruses sero-types 2 and 5 (Ad2 and Ad5) are linear duplex DNA molecules with molecular weights of 23 × 106 (Green et al. 1967; van der Eb et al. 1969) whose structure has been studied by cleavage with site-specific endonucleases.
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Mulder et al. (1974) studied this question.
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