The Essential Function of Protein-disulfide Isomerase Is to Unscramble Non-native Disulfide Bonds

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1A single polypeptide acts both as the beta subunit of prolyl 4-hydroxylase and as a protein disulfide-isomerase.1987 · 240 citations
2. 2The yeast EUG1 gene encodes an endoplasmic reticulum protein that is functionally related to protein disulfide isomerase.1992 · 154 citations
3. 3Molecular Structure of a Yeast Gene, PDI1, Encoding Protein Disulfide Isomerase That Is Essential for Cell Growth1991 · 56 citations
4. 4Expression and site-directed mutagenesis of human protein disulfide isomerase in Escherichia coli. This multifunctional polypeptide has two independently acting catalytic sites for the isomerase activity.1992 · 147 citations
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