Why the study?
Does angiotensin II receptor blockade reduce tachycardia-induced atrial adhesion molecule expression?
Does angiotensin II receptor blockade reduce tachycardia-induced atrial adhesion molecule expression?
Angiotensin II receptor blockade attenuates tachycardia-induced endocardial VCAM-1 expression, suggesting a mechanism for reducing prothrombotic endocardial remodeling in atrial fibrillation.
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May attenuate atrial prothrombotic remodeling; hypothesis-generating in animal models and leaves clinical translation in AF open.
Goette et al. (2008) studied this question.
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