Why the study?
Severe AS induces adverse LV and LA remodeling with increased risk of AF, warranting a review of these changes before and after aortic valve replacement and the role of myocardial strain analysis.
Does speckle-tracking echocardiography accurately assess left atrial remodeling and predict clinical outcomes in patients with severe aortic stenosis undergoing aortic valve replacement?
Does speckle-tracking echocardiography accurately assess left atrial remodeling and predict clinical outcomes in patients with severe aortic stenosis undergoing aortic valve replacement?
Speckle-tracking echocardiography, particularly peak atrial longitudinal strain, is a sensitive and prognostic tool for evaluating left atrial remodeling and predicting arrhythmias in patients undergoing aortic valve replacement for severe aortic stenosis.
Severe aortic stenosis (AS) is the most common valve disease in the elderly and is associated with poor prognosis if treated only medically. AS causes chronic pressure overload, concentric left ventricular (LV) hypertrophy, myocardial stiffness, and diastolic dysfunction. This adverse remodeling also affects the left atrium (LA), which dilates and develops myocardial fibrosis, with a reduction in intrinsic function and a consequent high risk of the development of atrial fibrillation. Speckle-tracking echocardiography is able to detect myocardial dysfunction before other conventional parameters, such as LV ejection fraction, and also predict clinical outcomes. This review aims at describing LV and LA remodeling in AS and before and after aortic valve replacement and the usefulness of myocardial strain analysis in this clinical setting.
No takes yet. Share an insight, caveat, or question.
Lisi et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: