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January 1, 1998Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology

In Vitro Selection of HIV-1 Resistant to an Anti-CD4 Monoclonal Antibody That Inhibits Virus Transcription

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Authors

NCNolwenn CoudronnièreLa Jolla Institute for ImmunologyCDClaudine DavidCentre National de la Recherche ScientifiqueMHM. HirnUniversité Claude Bernard Lyon 1

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Cite This Study

Coudronnière et al. (1998) studied this question.

synapsesocial.com/papers/6a1cd7c75a7763abe789cf7dhttps://doi.org/10.1097/00042560-199801010-00003
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1An antibody that binds domain 1 of CD4 inhibits replication of HIV-1, but not HTLV-I, in a CD4-positive/p56lck-negative HTLV-I-transformed cell line1996 · 26 citations
  2. 2Pilot phase I study using zidovudine in association with a 10-day course of anti-CD4 monoclonal antibody in seven AIDS patients1989 · 21 citations
  3. 3Ig CDR3-like region of the CD4 molecule is involved in HIV-induced syncytia formation but not in viral entry1993 · 60 citations
  4. 4Signals Transduced through the CD4 Molecule on T-Lymphocytes Activate NF-κB1994 · 42 citations
  5. 5Chemically selected subclones of the CEM cell line demonstrate resistance to HIV-1 infection resulting from a selective loss of NF-kappa B DNA binding proteins.1994 · 25 citations