February 3, 2004Circulation
Atrial Fibrillation Originating From Persistent Left Superior Vena Cava
Why the study?
The persistent left superior vena cava (LSVC) has been associated with organized arrhythmias but not previously with atrial fibrillation (AF) as an arrhythmogenic source.
Does catheter ablation of connections to a persistent left superior vena cava prevent atrial fibrillation in patients with ectopy originating from this structure?
Population
5 patients with symptomatic drug-refractory AF and ectopy from persistent LSVC
Comparison
Catheter ablation targeting LSVC connections to lateral left atrium and coronary sinus
Design
Case series
Follow-up
15+/-10 months
Authors
Discussion
Loading...
Member takes
Implication
Supports PLSVC isolation in refractory AF with ectopy from this site; leaves open need for prospective trials.
Structured PICO
Does catheter ablation of connections to a persistent left superior vena cava prevent atrial fibrillation in patients with ectopy originating from this structure?
P
Population
5 patients with symptomatic drug-refractory atrial fibrillation and ectopy from the persistent left superior vena cava (LSVC) observed after pulmonary vein isolation (mean age 46+/-11 years, 4 men).
I
Intervention
Catheter ablation in the LSVC targeting electrical connections to the lateral left atrium and coronary sinus.
O
Outcome
Electrical isolation of the LSVC and maintenance of sinus rhythm without antiarrhythmic drugs.
A persistent left superior vena cava can be an arrhythmogenic source of atrial fibrillation, and catheter ablation of its connections to the atria can successfully isolate it and maintain sinus rhythm.
Cite This Study
Hsu et al. (2004) studied this question.