Why the study?
Should antihypertensive medication use be reduced or withdrawn in nursing home patients?
Should antihypertensive medication use be reduced or withdrawn in nursing home patients?
The management of hypertension, including the potential withdrawal or dose reduction of antihypertensive medications, should be reevaluated in nursing home patients due to uncertain benefits and unique risks of adverse effects.
Antihypertensive deprescribing lacks evidence in nursing home patients; leaves open the risk-benefit balance and need for targeted trials.
Of the 1.5 million nursing home residents, about 40% are aged 85 years or older, and a similar percentage have hypertension. The rates of incorrect diagnoses from the "white coat" effect and from errors in blood pressure evaluation are as frequent in older persons as in younger persons. The benefits of antihypertensive treatment and the risks of lowering blood pressures in the very old (> or = 85 years) are uncertain. Elderly patients experience adverse effects from drug treatment that are unique to their age group and that complicate management problems associated with polypharmacy and multiple comorbid conditions. Trials to withdraw or lower the dosage of antihypertensive medications have been successful in up to 40% of elderly persons when combined with salt restriction and weight loss, but such studies are lacking in nursing home patients. The management of hypertension should be reevaluated in nursing home patients.
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Paul Froom (2000) studied this question.
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