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Background: Apathy is one of the most prevalent neuropsychiatric symptoms encountered in Alzheimer's disease (AD) and may be an early sign in the development of dementia persisting over the disease course. It has been associated with poor disease outcome, impaired daily functioning, and significant caregiver distress. Early diagnosis and timely treatment of apathy in AD are of great importance. However, approved agents for apathy are still missing.
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Theleritis et al. (2019) studied this question.
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